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Test Code Billings Clinic: 4954 Mayo: HIBS Haemophilus influenzae Type B Antibody, IgG, Serum

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

Haemophilus influenzae B Ab, IgG, S


Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Specimen Type

Serum

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Reference Values

≥0.15 mg/L

Reference values apply to all ages.

Day(s) and Time(s) Performed

Tuesday, Thursday; 8 a.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86684

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HIBS Haemophilus influenzae B Ab, IgG, S 11257-3

 

Result ID Test Result Name Result LOINC Value
83261 Haemophilus influenzae B Ab, IgG, S 11257-3

Useful For

Assessing a patient's immunological (IgG) response to Haemophilus influenzae type B (HIB) vaccine

 

Assessing immunity against HIB

 

Aiding in the evaluation of immunodeficiency

Interpretation

An anti-Haemophilus influenzae type B (HIB) IgG antibody concentration of 0.15 mg/L is generally accepted as the minimum level for protection at a given time; however, it does not confer long-term protection. A study from Finland suggested that the optimum protective level is 1.0 mg/L postimmunization.(1) Furthermore, studies have shown that the response to HIB vaccine is age-related.

 

By testing pre- and postvaccination patient serum specimens, this test may be used to aid diagnosis of immunodeficiency.