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Test Code Billings Clinic: 8944 Mayo: MUR Lysozyme (Muramidase), Plasma

Reporting Name

Lysozyme (Muramidase), P

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Confirming marked increases in the granulocyte or monocyte pools as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis


Following the course of therapy in cases of chronic granulocytic or chronic monocytic leukemias

Method Name


Specimen Required

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions:

1. Centrifuge and transfer plasma to a  plastic vial within 2 hours of collection.

2. Freeze immediately after transferring.

Specimen Type

Plasma EDTA

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen 30 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Reference Values

≥12 months: 2.7-9.4 mcg/mL

Reference values have not been established for patients who are <12 months of age.


Levels >200 mcg/mL may be seen in acute nonlymphocytic leukemia (M2, M4, M5) or chronic granulocytic leukemias.

Day(s) and Time(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
MUR Lysozyme (Muramidase), P 2589-0


Result ID Test Result Name Result LOINC Value
MUR Lysozyme (Muramidase), P 2589-0