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Test Code LBC Lamellar Body Count, Amniotic Fluid

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Sysmex XN-9000, Platelet Count by Impedance Method

Reporting Name

Lamellar Body Count, AF

Specimen Required

Container/Tube: Amniotic fluid container or plastic vial

Specimen Volume: 2 mL

Collection Instructions:

1. Do not centrifuge

2. Amniotic specimens must be blood and meconium free.

Specimen Type

Amniotic Fld

Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Amniotic Fld Refrigerated (preferred) 28 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Other Centrifuged specimen. Presence of blood or meconium

Reference Values

Immature: <15,000/mcL

Indeterminate: 15,000-50,000/mcL

Mature: >50,000/mcL


Cutoffs are based on consensus protocol (Neerhof M, Dohnal JC, Ashwood ER, et al: Lamellar body counts: a consensus on protocol. Obstet Gynecol 2001;97:318-320)

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
LBC Lamellar Body Count, AF 19114-8


Result ID Test Result Name Result LOINC Value
LBCC Lamellar Body Count 19114-8
LBCI Interpretation 59462-2

Useful For

Predicting fetal lung maturity and assessing the risk of developing neonatal respiratory distress syndrome, when performed during 32 to 39 weeks gestation


Amniotic fluid lamellar body counts (LBC) above 50,000/mcL are predictive of fetal lung maturity.


Amniotic fluid LBC below 15,000/mcL are suggestive of fetal lung immaturity and increased risk of neonatal respiratory distress syndrome (RDS).


The main value of fetal lung maturity testing is predicting the absence of RDS. An immature test result for fetal lung maturity is less reliable in predicting the presence of RDS.(1)