Cytology, Bladder Washings, Kidney Drainage, Ureter Washings, Urethra Washings, or Urine
Performing Laboratory
Billings Clinic LaboratoryMethodology
Includes slide preparation by liquid prep method, routine Papanicolaou staining, and microscopic cytologic examination.Cytology studies are performed on urine sediment to detect malignant, premalignant, and other pathologic processes.
Specimen Requirements
1. Collect 30 mL from a random, midstream urine collection.2. Fix with an equal amount of cytology fixative.
3. Label specimen appropriately (patient’s name, history number, and specimen source) on the container—not the lid.
Note: 1. Recent instrumentation and calculi may produce atypical changes in urothelial cells simulating malignancy.
2. Please complete a “Reference Pathology/Non-Gynecologic Cytology Request Form” in “Request Forms” in “Special Instructions” including specimen source and all pertinent clinical data (clinical symptoms, history of malignancy, chemotherapy, radiation therapy, and tentative diagnosis), and forward it with the specimen.
Reference Values
Descriptive diagnosis of microscopic findings are generally categorized as positive, inconclusive, or negative for malignancy.Nondiagnostic or unsatisfactory results are given when material is inadequate for a diagnostic interpretation.