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Test Code AK1 Adenylate Kinase Enzyme Activity, Blood

Reporting Name

Adenylate Kinase, B

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of chronic nonspherocytic hemolytic anemia

Method Name

Kinetic Spectrophotometry


Specimen Required


Collection Container/Tube:

Preferred: Yellow top (ACD solution B)

Acceptable: Lavender top (EDTA) or yellow top (ACD solution A)

Specimen Volume: 6 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send whole blood specimen in original tube. Do not aliquot.


Specimen Type

Whole Blood ACD-B

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood ACD-B Refrigerated 20 days

Reject Due To

Gross hemolysis Reject
Fully clotted Reject

Reference Values

≥12 months: 195-276 U/g Hb

Reference values have not been established for patients younger than 12 months.

Interpretation

In adenylate kinase deficiency, values are expected to be less than 30% of normal mean, although this value should be interpreted in the context of age of the patient and other enzyme values.

Day(s) Performed

Tuesday, Thursday

Report Available

1 to 6 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82657

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AK1 Adenylate Kinase, B 44051-1

 

Result ID Test Result Name Result LOINC Value
AKCL Adenylate Kinase, B 44051-1

Forms

If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.