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Test Code Billings Clinic: 3994 Vancomycin, Random, Plasma or Serum

Important Note

This test can not be added on to a specimen that is already in the lab.  A new sample must be drawn.

Performing Laboratory

Billings Clinic Laboratory: Chemistry

Useful For

  • Monitoring adequacy of drug concentration during vancomycin therapy
  • This test is used whenever a specimen is submitted or collected without collection timing information. Random levels may be ordered when attempting to determine when to dose vancomycin in patients with renal impairment or those undergoing dialysis.



Particle-enhanced turbidimetric inhibition immunoassay (PETINIA)

Specimen Requirements

Submit only 1 of the following specimens:

Serum or plasma should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.



  • Draw blood in a green-top (lithium heparin) tube(s).
  • Spin down and send 1.0 mL of heparinized plasma frozen.



  • Draw blood in a plain, red-top tube(s) or a serum gel tube(s).
  • Spin down and send 1.0 mL of serum frozen


  • Vancomycin crystalline degradation product (CDP‑1) at 20 µg/mL CDP‑1 demonstrates crossreactivity at 0 and 10 µg/mL vancomycin of 21.0% and 19.1% respectively.


Specimen Type Temperature Time
Plasma, Serum Refrigerated 2 days
  Frozen (preferred) 1 month
  Ambient 8 hours


Reference Values

Vancomycin Critical Range:

>60.0 ug/mL

Day(s) Test Set Up


Test Classification and CPT Coding

80202 - Vancomycin

LOINC Code Information

Reporting Name LOINC Code
Vancomycin, Random 20578-1