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Test Code Billings Clinic: 4355 Vancomycin, Trough, Plasma

Important Note

This test can not be added on to a specimen that is already in the lab.  A new sample must be drawn.

Additional Codes

Ordering Mnemonic
MayoAccess: BCL110

Performing Laboratory

Billings Clinic Laboratory: Chemistry

Useful For

Trough concentrations drawn at steady-state are the preferred test for monitoring vancomycin therapy


Particle-enhance turbidimetric inhibition immunoassay (PETINIA)

Specimen Requirements

  • Draw blood in a green-top (lithium heparin) tube(s).
  • Spin down and send 1 mL of heparinized plasma frozen in plastic vial.
  • Plasma for a trough level is usually drawn just prior to next dose,
  • Date and time of last dose are required on request form for processing.


Specimen Type Temperature Time
Plasma Refrigerated 8 hours
  Frozen (preferred) 2 months


Reference Values

Therapeutic concentration:  10.0 - 20.0 µg/mL

Skin and Soft Tissue, UTI: 10.0 - 15.0 ug/mL

Bacteremia, Endocarditis, Febrile Neutropenia, Pneumonia, Osteomyelitis, Meningitis: 15.0 - 20.0 ug/mL


Call back concentration:  < 5.0 or > 20.0  µg/mL

Day(s) Test Set Up


Test Classification and CPT Coding

80202 - Vancomycin

LOINC Code Information

Reporting Name LOINC Code
Vancomycin, Trough 4092-3