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Test Code RB24 Retinol-Binding Protein, 24 Hour, Urine

Reporting Name

Retinol-Binding Protein, 24-Hour, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessing renal tubular injury or dysfunction

 

Screening for other tubular abnormalities

 

Detecting chronic asymptomatic renal tubular dysfunction.(2)

Method Name

RBP1: Calculation

RBPCN: Immunonephelometry

CRT24: Enzymatic Colorimetric Assay


Necessary Information


24-hour volume (in milliliters) is required.



Specimen Required


Container/Tube: Plastic, 5-mL tube

Specimen Volume: 5 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. No preservative.

3. Mix well before taking 5-mL aliquot.

Additional Information:

See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Retinol-Binding Protein:

≥18 years of age: <273 mcg/24 hour

Reference values have not been established for patients who are less than 18 years.

 

Creatinine:

Males ≥18: 930-2955 mg/24 hours

Females ≥18: 603-1783 mg/24 hours

Reference values have not been established for patients who are less than 18 years.

Interpretation

Retinol-binding protein above the reference values may be indicative of a proximal tubular dysfunction.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

1 to 4 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83883

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RB24 Retinol-Binding Protein, 24-Hour, U 96399-1

 

Result ID Test Result Name Result LOINC Value
CR_A Creatinine, 24 HR, U 2162-6
RBP1 Retinol-Binding Protein, 24-Hour, U 18362-4
RBPCN Retinol-Binding Protein Conc 96406-4
TM27 Collection Duration (h) 13362-9
VL69 Urine Volume (mL) 3167-4
CR_24 Creatinine Concentration, 24 HR, U 20624-3

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Profile Information

Test ID Reporting Name Available Separately Always Performed
RBP1 Retinol-Binding Protein, 24-Hour, U No Yes
RBPCN Retinol-Binding Protein Conc No Yes
CRT24 Creatinine, 24 HR, U Yes, (order CTU) Yes

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

No

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

No

Boric Acid

OK

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No