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HelpTest Code RPR9 Respiratory Profile, Region 9, Great Plains (KS, ND, NE, SD), Serum
Reporting Name
Resp Profile, Reg 9, Great PlainsPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Assessing sensitization to various inhalant allergens commonly found in the Great Plains region including Kansas, North Dakota, Nebraska, and South Dakota
Defining the allergen responsible for eliciting signs and symptoms
Identifying allergens:
-Responsible for allergic response and/or anaphylactic episode
-To confirm sensitization prior to beginning immunotherapy
-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens
Method Name
Fluorescence Enzyme Immunoassay (FEIA)
Ordering Guidance
For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Type
SerumSpecimen Minimum Volume
1.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 90 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
Reference Values
Specific IgE:
|
Class |
IgE kU/L |
Interpretation |
|
0 |
<0.10 |
Negative |
|
0/1 |
0.10-0.34 |
Borderline/equivocal |
|
1 |
0.35-0.69 |
Equivocal |
|
2 |
0.70-3.49 |
Positive |
|
3 |
3.50-17.4 |
Positive |
|
4 |
17.5-49.9 |
Strongly positive |
|
5 |
50.0-99.9 |
Strongly positive |
|
6 |
≥100 |
Strongly positive |
Reference values apply to all ages.
Total IgE:
|
Age |
Reference interval (in kU/L) |
|
0-5 months |
≤13 |
|
6-11 months |
≤34 |
|
1 and 2 years |
≤97 |
|
3 years |
≤199 |
|
4-6 years |
≤307 |
|
7 and 8 years |
≤403 |
|
9-12 years |
≤696 |
|
13-15 years |
≤629 |
|
16 and 17 years |
≤537 |
|
18 years and older |
≤214 |
Interpretation
Elevated concentrations of total IgE may be found in a variety of clinical diseases, including allergic disease, certain primary immunodeficiencies, infections, inflammatory diseases, and malignancies.
Detection of allergen-specific IgE antibodies in serum (class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 3 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82785-IgE
86003 x 22-Each individual allergen
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| RPR9 | Resp Profile, Reg 9, Great Plains | 94593-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| ALTN | Alternaria Tenuis, IgE | 6020-2 |
| ASHW | White Ash, IgE | 6278-6 |
| ASP | Aspergillus Fumigatus, IgE | 6025-1 |
| BERG | Bermuda Grass, IgE | 6041-8 |
| BXMPL | Box Eld/Maple, S, IgE | 7155-5 |
| CAT | Cat Epithelium, IgE | 6833-8 |
| CED | Mountain Cedar, IgE | 6178-8 |
| CLAD | Cladosporium, IgE | 53760-5 |
| COCR | Cockroach, IgE | 6078-0 |
| CTWD | Cottonwood, IgE | 6090-5 |
| DF | House Dust Mites/D.F., IgE | 6095-4 |
| DOGD | Dog Dander, IgE | 6098-8 |
| DP | House Dust Mites/D.P., IgE | 6096-2 |
| ELM | Elm, IgE | 6109-3 |
| IGE | Immunoglobulin E (IgE), S | 19113-0 |
| MULB | Mulberry, IgE | 6281-0 |
| NETT | Nettle, IgE | 6186-1 |
| OAK | Oak, IgE | 6189-5 |
| PENL | Penicillium, IgE | 6212-5 |
| RUSS | Russian Thistle, IgE | 6234-9 |
| SORR | Red Sorrel, IgE | 6244-8 |
| SRW | Short Ragweed, IgE | 6085-5 |
| TIMG | Timothy Grass, IgE | 6265-3 |
Forms
If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| IGE | Immunoglobulin E (IgE), S | Yes | Yes |
| DP | House Dust Mites/D.P., IgE | Yes | Yes |
| DF | House Dust Mites/D.F., IgE | Yes | Yes |
| CAT | Cat Epithelium, IgE | Yes | Yes |
| DOGD | Dog Dander, IgE | Yes | Yes |
| BERG | Bermuda Grass, IgE | Yes | Yes |
| TIMG | Timothy Grass, IgE | Yes | Yes |
| COCR | Cockroach, IgE | Yes | Yes |
| PENL | Penicillium, IgE | Yes | Yes |
| CLAD | Cladosporium, IgE | Yes | Yes |
| ASP | Aspergillus Fumigatus, IgE | Yes | Yes |
| ALTN | Alternaria Tenuis, IgE | Yes | Yes |
| BXMPL | Box Eld/Maple, S, IgE | Yes | Yes |
| CED | Mountain Cedar, IgE | Yes | Yes |
| OAK | Oak, IgE | Yes | Yes |
| ELM | Elm, IgE | Yes | Yes |
| CTWD | Cottonwood, IgE | Yes | Yes |
| ASHW | White Ash, IgE | Yes | Yes |
| MULB | Mulberry, IgE | Yes | Yes |
| SRW | Short Ragweed, IgE | Yes | Yes |
| RUSS | Russian Thistle, IgE | Yes | Yes |
| SORR | Red Sorrel, IgE | Yes | Yes |
| NETT | Nettle, IgE | Yes | Yes |