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HelpTest Code A124 Alpha-1-Microglobulin, 24 Hour, Urine
Reporting Name
Alpha-1-Microglobulin, 24 HR, UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Assessment of renal tubular injury or dysfunction using 24-hour urine collections
Screening for tubular abnormalities
Detecting chronic asymptomatic renal tubular dysfunction(2)
Method Name
AIM, A1MCR: Calculation
A1MC: Immunonephelometry
CRT24: Enzymatic Colorimetric Assay
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Container/Tube: Plastic, 5-mL tube
Specimen Volume: 4 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. No preservative.
3. Mix well before taking 4-mL aliquot.
Additional Information: For multiple collections see Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens
Specimen Type
UrineSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 7 days | |
| Ambient | 7 days | ||
| Frozen | 7 days |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
≥18 years: <23 mg/24 hours
Reference values have not been established for patients who are less than 18 years of age.
Interpretation
Alpha-1-microglobulin above the reference values may be indicative of a proximal tubular dysfunction.
Day(s) Performed
Varies
Report Available
1 to 7 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
83883
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| A124 | Alpha-1-Microglobulin, 24 HR, U | 99075-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CR_A | Creatinine, 24 HR, U | 2162-6 |
| AIM | Alpha-1-Microglobulin, 24 HR, U | 48414-7 |
| A1MC | Alpha-1-Microglobulin Concentration | 99076-2 |
| A1MCR | A1M/Creat Ratio | 99075-4 |
| TM27 | Collection Duration (h) | 13362-9 |
| VL69 | Urine Volume (mL) | 3167-4 |
| CR_24 | Creatinine Concentration, 24 HR, U | 20624-3 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| AIM | Alpha-1-Microglobulin, 24 HR, U | No | Yes |
| A1MCR | A1M/Creat Ratio | No | Yes |
| A1MC | Alpha-1-Microglobulin Concentration | No | Yes |
| CRT24 | Creatinine, 24 HR, U | Yes, (Order CTU) | Yes |