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HelpTest Code A2M Alpha-2-Macroglobulin, Serum
Reporting Name
Alpha-2-Macroglobulin, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Evaluating patients with nephrotic syndrome and pancreatitis
Method Name
Nephelometry
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial
Specimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Reference Values
≤18 years: 178-495 mg/dL
>18 years: 100-280 mg/dL
Interpretation
Values are elevated in the nephrotic syndrome in proportion to the severity of protein loss (lower molecular weight).
Values are low in proteolytic diseases such as pancreatitis.
Day(s) Performed
Monday through Friday
Report Available
1 to 3 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
83883
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| A2M | Alpha-2-Macroglobulin, S | 1835-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| A2M | Alpha-2-Macroglobulin, S | 1835-8 |
Forms
If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.