Sign in →

Test Code ADMA Asymmetric Dimethylarginine, Plasma

Reporting Name

Asymmetric dimethylarginine, P

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessing the likelihood of future coronary events in patients with coronary heart disease, type II diabetes mellitus, or kidney disease

 

Prompting intervention and assessing improvements among subjects with elevated ADMA and hypercholesterolemia or type II diabetes mellitus

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)


Specimen Required


Patient Preparation: Fasting-overnight (12 hours)

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge and aliquot 1 mL of plasma into plastic vial.

2. Send specimen frozen.


Specimen Type

Plasma EDTA

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen (preferred) 90 days
  Ambient  7 days
  Refrigerated  7 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

≥18 years: 63-137 ng/mL

Reference values have not been established for patients who are <18 years of age

Interpretation

In patients with preexisting coronary conditions or at high risk for coronary events (diabetes, renal insufficiency), asymmetric dimethylarginine levels in the upper tertile, above 112 ng/mL, confer an increased risk for future coronary events.

Day(s) Performed

Thursday

Report Available

2 to 9 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ADMA Asymmetric dimethylarginine, P 80981-4

 

Result ID Test Result Name Result LOINC Value
83651 Asymmetric dimethylarginine, P 80981-4

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.