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Test Code ASNA Arsenic, Nails

Reporting Name

Arsenic, Nails

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detection of nonacute arsenic exposure in nail specimens

Method Name

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)


Necessary Information


Indicate source of nails (fingernails or toenails), if known.



Specimen Required


Supplies: Hair and Nails Collection Kit (T565)

Specimen Volume: 0.2 g

Collection Instructions:

1. Prepare and transport specimen per the instructions in the kit or see Collecting Hair and Nails for Metals Testing.

2. Clippings should be taken from all 10 fingernails or toenails.


Specimen Type

Nail

Specimen Minimum Volume

0.05 g

Specimen Stability Information

Specimen Type Temperature Time Special Container
Nail Ambient (preferred)
  Frozen 
  Refrigerated 

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

0-15 years: Not established

≥16 years: <1.0 mcg/g of nails

Interpretation

Nails grow at a rate of approximately 0.1 inch/month. Nail keratin synthesized today will grow to the distal end in approximately 6 months. Thus, a nail specimen collected at the distal end represents exposure of 6 months ago.

 

Nail arsenic above 1.0 mcg/g dry weight may indicate excessive exposure. It is normal for some arsenic to be present in nails, as everybody is exposed to trace amounts of arsenic from the normal diet.

 

The highest hair or nail arsenic observed at Mayo Clinic was 210 mcg/g dry weight in a case of chronic exposure that was the cause of death.

Day(s) Performed

Tuesday

Report Available

2 to 8 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82175

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ASNA Arsenic, Nails 8157-0

 

Result ID Test Result Name Result LOINC Value
2535 Arsenic, Nails 8157-0
ASNSC Specimen Source 31208-2