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Test Code BIllings Clinic: 8923 Mayo: LID Lidocaine, Serum

Reporting Name

Lidocaine, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessing optimal lidocaine dosing during the acute management of ventricular arrhythmias following myocardial infarction or during cardiac manipulation such as surgery

 

Assessing potential lidocaine toxicity

Method Name

Enzyme-Multiplied Immunoassay Technique (EMIT)


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum Red

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject

Reference Values

Therapeutic: 1.5-5.0 mcg/mL

Critical value: >6.0 mcg/mL

Interpretation

Optimal response to lidocaine occurs when the serum concentration is between 1.5 and 5.0 mcg/mL.

 

Toxicity is more likely when concentrations exceed 6.0 mcg/mL.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 2 days

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80176

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LID Lidocaine, S 3714-3

 

Result ID Test Result Name Result LOINC Value
8382 Lidocaine, S 3714-3

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.