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Test Code BUTAS Butalbital, Serum

Reporting Name

Butalbital, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring butalbital therapy

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS)


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions:

1. Draw blood immediately before the next scheduled dose.

2. Within 2 hours of collection centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum Red

Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Peak concentrations (100 mg single oral dose):

1.7-2.6 at 2 hours

1.3-1.7 at 24 hours

Toxic concentration: ≥10 mcg/mL

 

Cutoff concentrations by gas chromatography mass spectrometry:

Butalbital: 0.5 ng/mL

Interpretation

Butalbital concentrations of 10 mcg/mL or greater have been associated with toxicity.

Day(s) Performed

Thursday

Report Available

3 to 9 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BUTAS Butalbital, S 6895-7

 

Result ID Test Result Name Result LOINC Value
8427 Butalbital, S 6895-7

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.