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HelpTest Code Billings Clinic: 0232 Mayo: LDBF Lactate Dehydrogenase (LDH), Body Fluid
Reporting Name
Lactate Dehydrogenase (LD), BFPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Identification of exudative pleural effusions
Lactate dehydrogenase in pericardial fluids is not diagnostically useful.
Method Name
Photometric
Necessary Information
1. Date and time of collection are required.
2. Specimen source is required.
Specimen Required
Specimen Type: Body fluid
Preferred Source:
-Peritoneal fluid (peritoneal, abdominal, ascites, paracentesis)
-Pleural fluid (pleural, chest, thoracentesis)
-Drain fluid (drainage, Jackson Pratt [JP] drain)
-Pericardial
-Synovial
-Cerebral spinal fluid
Acceptable Source: Write in source name with source location (if appropriate)
Collection Container/Tube: Sterile container
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge to remove any cellular material and transfer into a plastic vial.
2. Indicate the specimen source and source location on label.
Specimen Type
Body FluidSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Body Fluid | Ambient (preferred) | 7 days | |
| Refrigerated | 48 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Anticoagulant or additive, Breast milk, nasal secretions, gastric secretions, bronchoalveolar lavage (BAL) or bronchial washings, colostomy/ostomy, feces, saliva, sputum, urine, or vitreous fluid | Reject |
Reference Values
An interpretive report will be provided.
Interpretation
Pleural fluid lactate dehydrogenase (LDH) to serum LDH ratios above 0.6 are most consistent with exudative effusions.(2,6)
Peritoneal fluid LDH above 220 U/L suggests secondary, rather than spontaneous bacterial peritonitis, in conjunction with other laboratory, imaging, and clinical findings.(4,5)
Synovial fluid LDH may be elevated greater than plasma or serum LDH due to inflammatory causes. Values should be interpreted in conjunction with other clinical findings.(7)
All other fluids: LDH may be used to differentiate transudative from exudative effusions. The decision limits are not well defined in fluids other than pleural fluid and should be interpreted in conjunction with other clinical findings.
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysTest Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83615
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LDBF | Lactate Dehydrogenase (LD), BF | 14803-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| LD_BF | Lactate Dehydrogenase (LD), BF | 14803-1 |
| FLD11 | Fluid Type, Lactate Dehydrogenase | 14725-6 |