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HelpTest Code Billings Clinic: 1192 PCR CSF Panel
Performing Laboratory
Billings Clinic Laboratory: Microbiology
Useful For
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Central nervous system (CNS) infections are responsible for causing inflammatory conditions of the brain and/or meningeal tissues surrounding the brain (i.e. meningitis, encephalitis and meningoencephalitis). Approximately 15% of cases are fatal and many other cases result in life-long disabilities such as loss of limbs, visual and hearing deficits, seizures, and altered learning and memory.
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The FilmArray Meningitis/Encephalitis (ME) Panel test is capable of the simultaneous detection and identification of multiple bacterial, viral and yeast nucleic acids directly from cerebrospinal fluid (CSF) specimens from patients with signs and/or symptoms of meningitis and/or encephalitis.
Methodology
Multiplex PCR
Specimen Requirements
- Cerebrospinal Fluid (CSF) collected via lumbar puncture
- Send refrigerated
- Minimum volume required: 0.5 mL
- Test as soon as possible (stable for 5 days)
- Do not centrifuge
Reference Values
Negative
Day(s) Test Set Up
Daily
Test Classification and CPT Coding
87798 X5 - E coli K1, Hemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus pneumoniae
87653 - Streptococcus agalactiae
87496 - Cytomegalovirus (CMV)
87498 - Enterovirus
87529 X2 - Herpes simplex virus (HSV-1) and Herpes Simplex Virus (HSV-2)
87532 - Human herpesvirus 6 (HHV-6)
87798 X2 - Human Parechovirus and Varicella zoster (VZV)
87798 - Cryptococcus neoformans/gatti
LOINC Code Information
| Reporting Name | LOINC Code |
| Escherichia coli K1 | 61398-4 |
| Haemophilus influenzae | 61366-1 |
| Listeria monocytogenes | 61369-5 |
| Neisseria meningitidis | 49671-1 |
| Streptococcus agalactiae | 48683-7 |
| Streptococcus pneumoniae | 49672-9 |
| Cytomegalovirus (CMV) | 30326-3 |
| Enterovirus | 29558-4 |
| Human herpesvirus 6 (HHV-6) | 33942-4 |
| Herpes simplex virus 1(HSV-1) | 16952-4 |
| Herpes simplex virus 2(HSV-2) | 16960-7 |
| Human parechovirus | 51669-0 |
| Varicella-zoster virus (VZV) | 21598-8 |
| Cryptococcus neoformans/gattii | 49098-7 |
Profile/Testing Information
Testing was performed using multiplex qualitative PCR for the detection of: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus, Herpes simplex virus (HSV-1), Herpes simplex virus (HSV-2), Human herpesvirus 6 (HHV-6), Human Parechovirus, Varicella zoster (VZV) and Cryptococcus neoformans/gatti.