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Test Code Billings Clinic: 1358 Mayo: SLFAT Cryptococcus Antigen Titer, Lateral Flow Assay, Serum

Reporting Name

Cryptococcus Ag Titer, LFA, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring Cryptococcus antigen titers in serum

 

Aiding in the diagnosis of cryptococcosis

 

This test should not be used as a test of cure or to guide treatment decisions.

Method Name

Lateral Flow Assay (LFA)


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial


Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Reference Values

Negative 

Reference values apply to all ages.

Interpretation

The presence of cryptococcal antigen in any body fluid (serum or cerebrospinal fluid) is indicative of cryptococcosis.

 

Disseminated infection is usually accompanied by a positive serum test.

 

Declining titers may indicate regression of infection. However, monitoring titers to cryptococcal antigen should not be used as a test of cure or to guide treatment decisions. Low-level titers may persist for extended periods of time following appropriate therapy and resolution of infection.(3,4)

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87899

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SLFAT Cryptococcus Ag Titer, LFA, S 9818-6

 

Result ID Test Result Name Result LOINC Value
62077 Cryptococcus Ag Titer, LFA, S 9818-6

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.