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Test Code Billings Clinic: 2235 Mayo: MACNT Macadamia Nut, IgE, Serum

Reporting Name

Macadamia Nut, IgE

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms

 

Testing also may be useful to identify allergens that may be responsible for allergic disease or an anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Method Name

Fluorescence Enzyme Immunoassay (FEIA)

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 0.5 mL for each 5 allergens requested

Additional Information: Designate specific allergens from the list in Allergens – Immunoglobulin E (IgE) Antibodies in Special Instructions.


Specimen Minimum Volume

For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Reference Values

Class

IgE kU/L

Interpretation

0

<0.35

Negative

1

0.35-0.69

Equivocal

2

0.70-3.49

Positive

3

3.50-17.4

Positive

4

17.5-49.9

Strongly positive

5

50.0-99.9

Strongly positive

6

≥100

Strongly positive

Reference values apply to all ages.

Interpretation

Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.

 

The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.

Day(s) and Time(s) Performed

Monday through Friday; 9 a.m.-8 p.m., Saturday; 8 a.m.-3 p.m.

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86003

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MACNT Macadamia Nut, IgE 11183-1

 

Result ID Test Result Name Result LOINC Value
MACNT Macadamia Nut, IgE 11183-1

Forms

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.