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HelpTest Code Billings Clinic: 2979 Quest: 16442 JC Polyoma Virus DNA, Quantitative, Real-Time PCR, CSF
Performing Laboratory
| Quest Diagnostics Infectious Disease, Inc. |
Useful For
JC Polyoma Virus (JCV) is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC Polyoma Virus DNA in CSF. Detection of the virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.
Methodology
Real-Time Polymerase Chain Reaction (RT-PCR)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Specimen Requirements
Preferred Specimen(s)
0.7 mL CSF
Minimum Volume
0.3 mL
Collection Instructions
Collect in a sterile, leak-proof container
Transport Container
Sterile, leak-proof container
Transport Temperature
Frozen
Storage/Stability
| Specimen Type | Temperature | Time |
| CSF | Ambient | 48 hours |
| Refrigerated | 7 days | |
| Frozen (preferred) | 30 days |
Reference Values
<500 copies/mL
Day(s) Test Set Up
Monday - Saturday
Test Classification and CPT Coding
87799
LOINC Code Information
| Reporting Name | LOINC Code |
| JC POLYOMA VIRUS DNA, QN REAL TIME PCR, CSF | 49410-4 |