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Test Code Billings Clinic: 4009 Creatinine, Plasma or Serum

Performing Laboratory

Billings Clinic Laboratory: Chemistry

Useful For

Creatinine:

  • Diagnosing and monitoring treatment of acute and chronic renal diseases
  • Adjusting dosage of renally excreted medications
  • Monitoring renal transplant recipients

Glomerular Filtration Rate (GFR):

  • Serum creatinine measurement is used in estimating GFR for people with chronic kidney disease (CKD) and those with risk factors for CKD (diabetes, hypertension, cardiovascular disease, and family history of kidney disease).

Methodology

Modified Jaffe Method

 

Specimen Requirements

Submit only 1 of the following specimens:

Serum or plasma should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.

 

Plasma

  • Draw blood in a green-top (lithium heparin) tube(s).
  • Spin down and send 1.0 mL of heparinized plasma frozen.

 

Serum

  • Draw blood in a plain, red-top tube(s) or a serum gel tube(s).
  • Spin down and send 1.0 mL of serum frozen

Storage/Stability

Specimen Type Temperature Time
Plasma, Serum Refrigerated 7 days
  Frozen (preferred) 3 months
  Ambient 24 hours

 

Reject Due To

  • Gross hemolysis
  • Gross icterus
  • Gross lipemia

Reference Values

Males:     

0 - 1 month                             0.3 - 1.0 mg/dL

1 - 12 months                         0.2 - 0.4 mg/dL

12 months - 11 years             0.3 - 0.7 mg/dL

11 - 17 years                          0.5 - 1.0 mg/dL

> 17 years                              0.8 - 1.5 mg/dL


Females: 

0 - 1 month                             0.3 - 1.0 mg/dL

1 - 12 months                         0.2 - 0.4 mg/dL

12 months - 11 years             0.3 - 0.7 mg/dL

11 - 17 years                          0.5 - 1.0 mg/dL

> 17 years                              0.6 - 1.2 mg/dL

Day(s) Test Set Up

Daily

Test Classification and CPT Coding

82565 - Creatinine; blood

LOINC Code Information

Reporting Name LOINC Code
Creatinine, Blood 2160-0
GFR, Non-African American 48642-3

Interferences

  • Unconjugated bilirubin at 15 mg/dL decreases the creatinine result in serum/plasma at 1.62 mg/dL by -13.4%.
  • Unconjugated bilirubin at 20 mg/dL decreases the creatinine result in serum/plasma at 5.32 mg/dL by -16.1%.
  • Glucose at 332 mg/dL increases the creatinine result in serum/plasma at 1.61 mg/dL by 10.6%.
  • Cefoxitin at 5.0 mg/dL increases the creatinine result in serum/plasma at 1.53 mg/dL by 17.0%.
  • Pyruvate at 10.0 mg/dL increases the creatinine result in serum/plasma at 1.53 mg/dL by 17.6%. Dopamine at 100 mg/dL increases the creatinine result in serum/plasma at 1.53 mg/dL by 13.7%.
  • Total Protein at 12.0 mg/dL increases the creatinine result in serum/plasma at 1.71 mg/dL by 10.5%.