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Test Code Billings Clinic: 4050 Salicylate, Serum or Plasma

Important Note

Venipuncture should occur prior to Sulfapyridine administration due to the potential for falsely depressed results.

Venipuncture should occur prior to Sulfasalazine administration due to the potential for falsely elevated results.

Performing Laboratory

Billings Clinic Laboratory: Chemistry

Useful For

Assessing salicylate toxicity

Methodology

Salicylate Hydroxylase/NADH

 

Specimen Requirements

Submit only 1 of the following specimens:

Serum or plasma should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.

 

Plasma

  • Draw blood in a green-top (lithium heparin) tube(s).
  • Spin down and send 1.0 mL of heparinized plasma frozen.
  • Date and time of last dose and date and time of draw are required on request form for processing.

 

Serum

  • Draw blood in a plain, red-top tube(s) or a serum gel tube(s).
  • Spin down and send 1.0 mL of serum frozen
  • Date and time of last dose and date and time of draw are required on request form for processing.

Storage/Stability

Specimen Type Temperature Time
Serum, Plasma Refrigerated (preferred) 14 days
  Frozen 6 months
  Ambient 7 days

 

Reject Due To

  • Gross icterus
  • Gross lipemia
  • Gross hemolysis

Reference Values

Therapeutic concentration:  2.8 - 20.0 mg/dL
Call-back toxic concentration value:  >30.0 mg/dL

Day(s) Test Set Up

Daily

Test Classification and CPT Coding

80307 - Drug test(s), presumptive, any number of drug classes

LOINC Code Information

Reporting Name LOINC Code
Salicylate 4024-6