Test Code Billings Clinic: 4314 Valproic Acid, Plasma or Serum
Performing Laboratory
Billings Clinic Laboratory: Chemistry
Useful For
- Monitoring total valproic acid in therapy
- Assessing compliance
- Evaluating potential toxicity
Methodology
Particle-enhance turbidimetric inhibition immunoassay (PETINIA)
Specimen Requirements
Submit only 1 of the following specimens:
Serum or plasma should be physically separated from cells as
soon as possible with a maximum limit of two hours from the time of
collection.
Plasma
- Draw blood in a green-top (lithium heparin) tube(s).
- Spin down and send 1 mL of heparinized plasma frozen in plastic vial.
- Date and time of last dose and date and time of draw are required on request form for processing.
- Indicate plasma on request form.
- Label specimen appropriately (plasma).
Serum
- Draw blood in a plain, red-top tube or a serum gel tube(s).
- Spin down and send 1 mL of serum frozen in plastic vial.
- Date and time of last dose and date and time of draw are required on request form for processing.
- Indicate serum on request form.
- Label specimen appropriately (serum).
Storage/Stability
Specimen Type | Temperature | Time |
Plasma, Serum | Refrigerated | 2 days |
Frozen (preferred) | 1 month | |
Ambient | 8 hours |
Reference Values
Therapeutic concentration: 50-100 µg/mL
Call-back toxic concentration
value: ≥120 µg/mL
Day(s) Test Set Up
Daily
Test Classification and CPT Coding
80164 - Valproic acid (dipropylacetic acid); total
LOINC Code Information
Reporting Name | LOINC Code |
Valproic Acid | 4086-5 |