Test Code Billings Clinic: 4360 Tobramycin, Peak, Plasma or Serum
Performing Laboratory
Billings Clinic Laboratory: Chemistry
Useful For
Monitoring adequacy of serum concentration during tobramycin therapy
Methodology
Particle-enhance turbidimetric inhibition immunoassay (PETINIA)
Specimen Requirements
Submit only 1 of the following specimens:
Serum or plasma should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.
Plasma
- Draw blood in a green-top (lithium heparin) tube(s).
- Spin down and send 1.0 mL of heparinized plasma frozen.
- Plasma for a peak level should be drawn 30 to 45 minutes after completion of infusion of an intravenous dose.
- Date and time of last dose are required on request form for processing.
Serum
- Draw blood in a plain, red-top tube(s) or a serum gel tube(s).
- Spin down and send 1.0 mL of serum frozen
- Plasma for a peak level should be drawn 30 to 45 minutes after completion of infusion of an intravenous dose.
- Date and time of last dose are required on request form for processing.
Storage/Stability
Specimen Type | Temperature | Time |
Plasma, Serum | Refrigerated | 3 days |
Frozen (preferred) | 1 month | |
Ambient | 8 hours |
Reject Due To
- Specimens stored at room temperature > 8 hours
- Hemolysis
Reference Values
Cystic Fibrosis: 20 - 35 ug/mL
Traditional Dosing: 8 - 12 ug/mL
Extended Interval Dosing: 20 - 25 ug/mL
Day(s) Test Set Up
Daily
Test Classification and CPT Coding
80200 - Tobramycin
LOINC Code Information
Reporting Name | LOINC Code |
Tobramycin, Peak | 4057-6 |
Tobra Dose Date/Time | 45285-4 |