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HelpTest Code Billings Clinic: 4822 Mayo: MYCO Mycoplasma pneumoniae Antibodies, IgG and IgM, Serum
Reporting Name
M. pneumoniae Ab, IgG and IgM, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Screening for recent or past exposure to Mycoplasma pneumoniae
This test should not be used as a screening procedure for the general population.
Method Name
MYCOG, MYCOM: Enzyme Immunoassay (EIA)
MMYCO: Indirect Immunofluorescence Assay (IFA)
MYCON: Interpretation
Ordering Guidance
Detection of IgM or IgG class antibodies to Mycoplasma pneumoniae provides exposure information. The preferred method of diagnosis of acute M pneumoniae infection is by molecular detection; order MPRP / Mycoplasma pneumoniae, Molecular Detection, PCR, Varies.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat inactivated specimen | Reject |
Reference Values
IgG: Negative
IgM: Negative
IgM by indirect immunofluorescence: Negative
Interpretation
|
IgG ELISA result |
IgM ELISA result |
Interpretation |
|
Positive |
Negative |
Results suggest past exposure. |
|
Positive
|
Reactive |
Prior exposure to Mycoplasma pneumoniae detected. Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay. |
|
Equivocal |
||
|
Negative |
Negative |
No antibodies to M pneumoniae detected. Acute infection cannot be ruled out as antibody levels may be below the limit of detection. If clinically indicated, a second serum should be submitted in 14 to 21 days. |
|
Negative |
Reactive |
No prior exposure to Mycoplasma pneumoniae. Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay.. |
|
Equivocal |
||
|
Equivocal |
Negative |
Recommend follow-up testing in 10 to 14 days if clinically indicated. |
|
Reactive |
Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay. |
|
|
Equivocal |
ELISA = Enzyme-linked immunosorbent assay
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 3 daysTest Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86738 x 2-Mycoplasma pneumoniae by EIA
86738-Mycoplasma pneumoniae by indirect IFA (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MYCO | M. pneumoniae Ab, IgG and IgM, S | 58733-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MYCOG | M. pneumoniae Ab, IgG, S | 45224-3 |
| MYCOM | M. pneumoniae Ab, IgM, S | 5257-1 |
| MYCON | M. pneumoniae Ab Interpretation | 69048-7 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MYCOG | M. pneumoniae Ab, IgG, S | No | Yes |
| MYCOM | M. pneumoniae Ab, IgM, S | No | Yes |
| MYCON | M. pneumoniae Ab Interpretation | No | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MMYCO | M. pneumoniae Ab, IgM, S by IFA | No | No |
Testing Algorithm
If the Mycoplasma pneumoniae IgM result is reactive or equivocal, then M pneumoniae IgM by indirect immunofluorescence assay will be performed at an additional charge.