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Test Code Billings Clinic: 4863 Athena: 112 NAbFeron® (IFNβ-1) Neutralizing Antibody, Serum

Performing Laboratory

Athena Diagnostics, Inc.

Useful For

Detection of neutralizing antibodies to interferon-beta in patients with Mulitple Sclerosis

Methodology

Viral Cytopathic Effect Assay

Specimen Requirements

Contact Billings Clinic Laboratory at 866-232-2522 prior to specimen draw for specific instructions.
 
It is imperative to follow specimen requirement directions. Due to time sensitivity, specimen must be drawn Monday through Thursday only and shipped the day of draw. Do not draw or transport specimen on weekends as Saturday deliver is NOT accepted.

  • Draw blood in plain, red-top tube(s).
  • Serum gel tube is acceptable.
  • Spin down and send 2 mL of serum refrigerated in plastic vial.

Specimen needs to be drawn either before treatment with interferon or >24 hours following the most recent dose. Patient should not be on steroid therapy for at least 2 weeks prior to testing.

Reference Values

Normal titer:  <20

Mild/moderate titer:  21-60

High titer:  >60

Day(s) Test Set Up

Tuesday, Wednesday

Test Classification and CPT Coding

86382 - neutralization test, viral

86384 - nitroblue tetrazolium dye test

87253 - definitive identification

Test Turnaround

14 - 21 days