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HelpTest Code Billings Clinic: 4898 Mayo: INSEC Stinging Insects Allergen Profile, Serum
Reporting Name
Stinging Insects Allergen ProfilePerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Establishing a diagnosis of an allergy to honeybee, yellow jacket, wasp, yellow faced hornet, and white-faced hornet venoms
Defining the allergen responsible for eliciting signs and symptoms
Identifying allergens:
-Responsible for allergic response and/or anaphylactic episode
-To confirm sensitization prior to beginning immunotherapy
-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens
Method Name
Fluorescence Enzyme Immunoassay (FEIA)
Ordering Guidance
For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Type
SerumSpecimen Minimum Volume
For 1 allergen: 0.3 mL
For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 90 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
Reference Values
|
Class |
IgE kU/L |
Interpretation |
|
0 |
<0.10 |
Negative |
|
0/1 |
0.10-0.34 |
Borderline/equivocal |
|
1 |
0.35-0.69 |
Equivocal |
|
2 |
0.70-3.49 |
Positive |
|
3 |
3.50-17.4 |
Positive |
|
4 |
17.5-49.9 |
Strongly positive |
|
5 |
50.0-99.9 |
Strongly positive |
|
6 |
≥100 |
Strongly positive |
Reference values apply to all ages.
Interpretation
Detection of IgE antibodies in serum (class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens responsible for eliciting signs and symptoms.
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.
Day(s) Performed
Monday through Friday
Report Available
Same day/1 day to 3 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86003 x 5
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| INSEC | Stinging Insects Allergen Profile | 94593-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| HBV | Honeybee Venom, IgE | 6844-5 |
| WFHV | White Faced Hornet Venom, IgE | 6280-2 |
| WSPV | Wasp Venom, IgE | 13176-3 |
| YFHV | Yellow Faced Hornet Venom, IgE | 6288-5 |
| YJV | Yellow Jacket Venom, IgE | 6740-5 |
Forms
If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HBV | Honeybee Venom, IgE | Yes | Yes |
| YJV | Yellow Jacket Venom, IgE | Yes | Yes |
| WSPV | Wasp Venom, IgE | Yes | Yes |
| YFHV | Yellow Faced Hornet Venom, IgE | Yes | Yes |
| WFHV | White Faced Hornet Venom, IgE | Yes | Yes |
Special Instructions
Testing Algorithm
This profile includes testing for honeybee, yellow jacket, wasp, yellow faced hornet, and white-faced hornet venoms.