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Test Code Billings Clinic: 7079 Thyroperoxidase (TPO) Antibodies, Plasma or Serum

Important Note

Performance of this assay has not been established with neonatal specimens.

Performing Laboratory

Billings Clinic Laboratory: Chemistry

Useful For

  • The detection of TPO antibodies can aid in predicting the progression of chronic thyroiditis.
  • TPO can be found in Hashimoto’s thyroiditis, Graves’ disease, and idiopathic hypothyroidism but are not diagnostic of these diseases.

Methodology

Chemiluminescent Immunoassay

Specimen Requirements

Submit only 1 of the following specimens:

Serum or plasma should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.

 

Plasma

  • Draw blood in a green-top (lithium heparin) tube(s).
  • Spin down and send 1.0 mL of heparinized plasma frozen.

 

Serum

  • Draw blood in a plain, red-top tube(s) or a serum gel tube(s).
  • Spin down and send 1.0 mL of serum frozen

Storage/Stability

Specimen Type Temperature Time
Plasma, Serum Refrigerated 2 days
  Frozen (preferred) 1 month
  Ambient 8 hours

 

Reject Due To

  • Specimens stored at room temperature > 8 hours
  • Gross hemolysis
  • Specimens frozen and thawed > 1 time

 

Reference Values

0 - 60 U/mL

Day(s) Test Set Up

Daily

Test Classification and CPT Coding

86376 - Microsomal antibodies (eg. thyroid or liver-kidney), each

LOINC Code Information

Reporting Name LOINC Code
TPO 56477-3