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Test Code Billings Clinic: 7350 Mayo: BARBU Barbiturates Confirmation, Random, Urine

Reporting Name

Barbiturates Confirmation, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detecting drug abuse involving barbiturates such as amobarbital, butalbital, pentobarbital, phenobarbital, and secobarbital

Method Name

Gas Chromatography Mass Spectrometry (GC-MS)


Ordering Guidance


For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order BARBX / Barbiturates Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, also order ADULT / Adulterants Survey, Random, Urine in addition to this test.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.


Specimen Type

Urine

Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To

Gross hemolysis OK
Gross icterus OK

Reference Values

Negative

 

Cutoff concentrations:

BUTALBITAL BY GC-MS

<100 ng/mL

 

AMOBARBITAL BY GC-MS

<100 ng/mL

 

PENTOBARBITAL BY GC-MS

<100 ng/mL

 

SECOBARBITAL BY GC-MS

<100 ng/mL

 

PHENOBARBITAL BY GC-MS

<100 ng/mL

Interpretation

The presence of a barbiturate in urine indicates use of one of these drugs.

 

Most of the barbiturates are fast acting; their presence indicates use within the past 3 days.

 

Phenobarbital, commonly used to control epilepsy, has a very long half-life. The presence of phenobarbital in urine indicates that the patient has used the drug sometime within the past 30 days.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

3 to 5 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80345

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BARBU Barbiturates Confirmation, U 53746-4

 

Result ID Test Result Name Result LOINC Value
21442 Butalbital-by GC/MS 16237-0
20642 Amobarbital-by GC/MS 16239-6
20643 Pentobarbital-by GC/MS 16240-4
20644 Secobarbital-by GC/MS 16238-8
20645 Phenobarbital-by GC/MS 16241-2
20651 Barbiturates Interpretation 69050-3
20647 Chain of Custody 77202-0

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.