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Test Code Billings Clinic: 7457 Mayo: SEAS Seasonal Inhalants Allergen Profile, Serum

Reporting Name

Seasonal Inhalants Allergen Profile

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Establishing a diagnosis of an allergy to seasonal inhalants

 

Defining the allergen responsible for eliciting signs and symptoms

 

Identifying allergens:

-Responsible for allergic response and/or anaphylactic episode

-To confirm sensitization prior to beginning immunotherapy

-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Method Name

Fluorescence Enzyme Immunoassay (FEIA)


Ordering Guidance


For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial 

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial. 


Specimen Type

Serum

Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Reference Values

Class

IgE kU/L

Interpretation

<0.10 

Negative 

0/1 

0.10-0.34 

Borderline/equivocal 

0.35-0.69 

Equivocal 

0.70-3.49 

Positive 

3.50-17.4 

Positive 

17.5-49.9 

Strongly positive 

50.0-99.9 

Strongly positive 

≥100 

Strongly positive 

Reference values apply to all ages.

Interpretation

Detection of IgE antibodies in serum (class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.

 

The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86003 x 10

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SEAS Seasonal Inhalants Allergen Profile 94593-1

 

Result ID Test Result Name Result LOINC Value
BIR Silver Birch, IgE 15283-5
BXMPL Box Eld/Maple, S, IgE 7155-5
EGPL English Plantain, IgE 6110-1
ELM Elm, IgE 6109-3
JUNE June Grass, IgE 6153-1
LAMQ Lambs Quarter, IgE 6156-4
OAK Oak, IgE 6189-5
RYEG Rye Grass, IgE 7369-2
SRW Short Ragweed, IgE 6085-5
TIMG Timothy Grass, IgE 6265-3

Forms

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.

Profile Information

Test ID Reporting Name Available Separately Always Performed
RYEG Rye Grass, IgE Yes Yes
JUNE June Grass, IgE Yes Yes
SRW Short Ragweed, IgE Yes Yes
EGPL English Plantain, IgE Yes Yes
LAMQ Lambs Quarter, IgE Yes Yes
BXMPL Box Eld/Maple, S, IgE Yes Yes
OAK Oak, IgE Yes Yes
ELM Elm, IgE Yes Yes
TIMG Timothy Grass, IgE Yes Yes
BIR Silver Birch, IgE Yes Yes