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HelpTest Code Billings Clinic: 7691 Mayo: MMPGM Mumps Virus Antibody, IgM and IgG, Serum
Reporting Name
Mumps Ab, IgM and IgG, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Diagnosis of mumps virus infection
Determination of postimmunization immune response of individuals to the mumps vaccine
Documentation of previous infection with mumps virus in an individual with no previous record of immunization to mumps virus
Method Name
MMPM: Enzyme Immunoassay (EIA)
MPPG: Multiplex Flow Immunoassay
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Specimen Type
SerumSpecimen Minimum Volume
0.9 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat-inactivated specimen | Reject |
Reference Values
IgM:
Negative: Index value 0.00-0.79
Reference value applies to all ages.
IgG:
Vaccinated: Positive (≥1.1 AI)
Unvaccinated: Negative (≤0.8 AI)
Reference values apply to all ages.
Interpretation
A positive IgG result coupled with a positive IgM result suggests recent infection with mumps virus. This result should not be used alone to diagnose mumps infection and should be interpreted in the context of clinical presentation.
A positive IgG result coupled with a negative IgM result indicates previous vaccination to or infection with mumps virus. These individuals are considered to have protective immunity to reinfection.
A negative IgG result coupled with a negative IgM result indicates the absence of prior exposure to mumps virus and nonimmunity. However, a negative result does not rule-out mumps infection or response to vaccination. The specimen may have been collected before the appearance of detectable antibodies. Negative results in suspected early mumps infection or within a week following vaccination should be followed by testing a new serum specimen in 2 to 3 weeks.
Equivocal results should be followed up with testing of a new serum specimen within 10 to 14 days.
Day(s) Performed
MMPM: Tuesday
MPPG: Monday through Saturday
Report Available
1 to 7 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86735-Mumps, IgG
86735-Mumps, IgM
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MMPGM | Mumps Ab, IgM and IgG, S | 77250-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MUMP1 | Mumps Ab, IgM, S | 6478-2 |
| MUMG | Mumps Ab, IgG, S | 6476-6 |
| DEXM | Index Value | 25419-3 |
| DEXG5 | Mumps IgG Antibody Index | 25418-5 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MMPM | Mumps Ab, IgM, S | Yes | Yes |
| MPPG | Mumps Ab, IgG, S | Yes | Yes |