Test Code Billings Clinic: 7971 Mayo: FNEU Neurotransmitter Metabolites (5HIAA, HVA, 3OMD) (CSF)
Reporting Name
Neurotransmitter MetabolitesPerforming Laboratory
Medical Neurogenetics, LLCMethod Name
HPLC-Electrochemistry
Specimen Required
Medical Neurogenetics collection kit (MCL Supply T657) required.
Each collection kit contains 5 microcentrifuge tubes.
COLLECTION PROTOCOL:
1) CSF should be collected from the first drop into the tubes in the numbered order. Fill each tube to the marked line with the required volumes
Tube 1: 0.5 mL
Tube 2: 1.0 mL
Tube 3: 1.0 mL (contains antioxidants necessary to protect the sample integrity)
Tube 4: 1.0 mL
Tube 5: 1.0 mL
- If sample's not blood contaminated, the tubes should be placed on dry ice at bedside
- If sample's are blood contaminated, the tubes should immediately be centrifuged (prior to freezing) and the clear CSF transferred to new similarly labeled tubes, then frozen
- Store samples at -80 until they can be shipped
2) Complete Medical Neurogenetics, LLC request form. Include test required, sample date and date of birth.
3) Label tubes with patient name and ID number, leaving the tube number viewable.
4) Place samples inside a specimen transport bag and the Medical Neurogenetics, LLC request form inside the pouch of the transport bag.
5) Ship samples frozen on dry ice.
Specimen Type
CSFSpecimen Minimum Volume
4.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
CSF | Frozen | CSF KIT |
Reject Due To
Specimens other than | CSF in special collection kit (MCL supply T657) |
Anticoagulants other than | NA |
Hemolysis | NA |
Lipemia | NA |
Icteric | NA |
Reference Values
Age 5HIAA HVA 3-O-MD
(years) (nmol/L) (nmol/L) (nmol/L)
0-0.2 208-1159 337-1299 <300
0.2-0.5 179-711 450-1132 <300
0.5-2.0 129-520 294-1115 <300
2.0-5.0 74-345 233-928 <150
5.0-10 66-338 218-852 <100
10-15 67-189 167-563 <100
Adults 67-140 145-324 <100
Interpretation performed by Keith Hyland, Ph.D.
Note: If test results are inconsistent with the clinical presentation, please call our laboratory to discuss the case and/or submit a second sample for confirmatory testing.
Day(s) Performed
Monday through Friday
Report Available
10 to 18 daysCPT Code Information
82542
83497
83150
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
FNEU | Neurotransmitter Metabolites | Not Provided |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
Z0852 | 5-Hydroxyindoleacetic acid | 47544-2 |
Z0849 | Homovanillic acid | 40846-8 |
Z0850 | 3-O-methyldopa | 34596-7 |
Z0851 | Interpretation: | 59462-2 |