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Test Code Billings Clinic: 8008 Mayo: PEANT Peanut, IgE with Reflex to Peanut Components, IgE, Serum

Reporting Name

Peanut Component Reflex, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluating patients with suspected peanut allergy

 

Evaluating patients with possible peanut cross-reactivity

Method Name

Fluorescent Enzyme Immunoassay (FEIA)


Ordering Guidance


For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Class

IgE kU/L

Interpretation

0

<0.10

Negative

0/1

0.10-0.34

Borderline / Equivocal

1

0.35-0.69

Equivocal

2

0.70-3.49

Positive

3

3.50-17.4

Positive

4

17.5-49.9

Strongly positive

5

50.0-99.9

Strongly positive

6

≥100

Strongly positive

 

Concentrations of 0.70 kU/L or more (class 2 and above) will flag as abnormally high.

Reference values apply to all ages.

Interpretation

When detectable total peanut IgE antibody is present (≥0.10 IgE kUa/L), additional specific component IgE antibody testing will be performed. If at least one potential specific allergenic peanut component IgE is detectable (≥0.10 IgE kUa/L), an interpretative report will be provided.

 

When the sample is negative for total peanut IgE antibody (<0.10 IgE kUa/L), further testing for specific peanut component IgE antibodies will not be performed. Negative IgE results for total peanut antibody may indicate a lack of sensitization to potential peanut allergenic components.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86003

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PEANT Peanut Component Reflex, S 6206-7

 

Result ID Test Result Name Result LOINC Value
PNUT Peanut, IgE, S 6206-7

Forms

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
PNTCP Peanut Components, IgE, S No No

Testing Algorithm

Testing begins with analysis of peanut IgE. If peanut IgE is negative (<0.10 kU/L), testing is complete.

 

If peanut IgE is 0.10 kU/L or greater, then 7 peanut components (Ara h 2, Ara h 1, Ara h 3, Ara h 6, Ara h 8, Ara h 9, and profilin Bet v2) are performed at an additional charge.