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HelpTest Code Billings Clinic: 8036 Mayo: INHA Inhibin A, Tumor Marker, Serum
Reporting Name
Inhibin A, Tumor Marker, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Aiding in the diagnosis of patients with granulosa cell tumors of the ovary when used in combination with inhibin B
Monitoring of patients with granulosa cell tumors and epithelial mucinous-type tumors of the ovary known to secrete inhibin A
Method Name
Immunoenzymatic Assay
Ordering Guidance
For the initial evaluation of patients suspected of having a granulosa cell tumor of the ovary, order INHAB / Inhibin A and B, Tumor Marker, Serum. If the results of the profile show that either inhibin A or B are elevated, consider monitoring the patient with the individual tests, INHA / Inhibin A, Tumor Marker, Serum or INHB / Inhibin B, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 90 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Males: <5.0 pg/mL
Females
<11 years: <5.0 pg/mL
11-17 years: <98 pg/mL
Premenopausal: <98 pg/mL
Postmenopausal: <5.0 pg/mL
Interpretation
Inhibin A levels are elevated in approximately 70% of patients with granulosa cell tumors and in approximately 20% of patients with epithelial ovarian tumors. A normal inhibin A level does not rule out a mucinous or granulosa ovarian cell tumor. Testing for inhibin B in these cases might be informative as a higher proportion of mucinous or granulosa ovarian cell tumors will have an elevated inhibin B level. Consider ordering INHAB / Inhibin A and B, Tumor Marker, Serum.
For monitoring of patients with known ovarian cancer, inhibin A levels decrease shortly after surgery. Elevations of inhibin A after treatment are suggestive of residual, recurrent, or progressive disease. In patients with recurrent disease, inhibin A elevation seems to be present earlier than clinical symptoms. Patients in remission show normal levels of inhibin A.
Day(s) Performed
Monday through Saturday
Report Available
1 to 3 daysTest Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86336
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| INHA | Inhibin A, Tumor Marker, S | 23883-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| INHA | Inhibin A, Tumor Marker, S | 23883-2 |
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.