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HelpTest Code Billings Clinic: 8079 Mayo: ALU Aluminum, 24 Hour, Urine
Reporting Name
Aluminum, 24 Hr, UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Monitoring aluminum exposure
Preferred matrix for assessment of exposure in patients with normal kidney function since rapidly filtered by kidneys
Monitoring metallic prosthetic implant wear
This test is not an acceptable substitute for serum aluminum measurements and is not recommended for routine aluminum screening.
Method Name
Dynamic Reaction Cell Inductively Coupled Plasma Mass Spectrometry (DRC-ICP-MS)
Ordering Guidance
The recommended test for routine aluminum screening is AL / Aluminum, Serum.
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert
Submission Container/Tube: Plastic urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. See Metals Analysis Specimen Collection and Transport for complete instructions.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Type
UrineSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
0-17 years: Not established
≥18 years: <13 mcg/24 hours
Interpretation
Daily excretion greater than 10 mcg/24 hours indicates exposure to excessive amounts of aluminum. In kidney failure, the ability of the kidney to excrete aluminum decreases, while the exposure to aluminum increases (aluminum-laden dialysis water, aluminum-laden albumin, and aluminum-laden phosphate binders).
Patients receiving chelation therapy with desferrioxamine (for iron- or aluminum-overload states) also excrete considerably more aluminum in their urine than normal.
Prosthesis wear is known to result in increased circulating concentration of metal ions.(1) Modest increase (10-20 mcg/24 hours) in urine aluminum concentration is likely to be associated with a prosthetic device in good condition. Urine concentrations above 50 mcg/ 24 hours in a patient with an aluminum-based implant and not undergoing dialysis, suggests significant prosthesis wear. Increased urine trace element concentrations in the absence of corroborating clinical information do not independently predict prosthesis wear or failure.
Day(s) Performed
Tuesday
Report Available
2 to 8 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82108
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ALU | Aluminum, 24 Hr, U | 26707-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8828 | Aluminum, 24 Hr, U | 26707-0 |
| TM15 | Collection Duration | 13362-9 |
| VL13 | Urine Volume | 3167-4 |