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Test Code Billings Clinic: 8209 Hepatitis Bc Antibody, Total (Anti-HBc, Total), Serum

Performing Laboratory

Billings Clinic Laboratory: Chemistry

 

See “Viral Hepatitis Serologic Profiles—Billings Clinic Laboratory” under Resources

Useful For

  • Diagnosis of recent or past hepatitis B infection
  • Determination of occult hepatitis B infection in otherwise healthy hepatitis B virus (HBV) carriers with negative test results for hepatitis B surface antigen, antihepatitis B surface, antihepatitis B core IgM, hepatitis Be antigen, and anti-HBe.
  • This assay is not useful for differentiating among acute, chronic, and past/resolved hepatitis B infection.
  • This assay is FDA-approved for in vitro diagnostic use and not for screening cell, tissue, and blood donors.

Methodology

Chemiluminescent Microparticle Immunoassay (CMIA)

Specimen Requirements

Serum should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.

 

  • Draw blood in a serum gel tube(s).
  • Spin down and send 0.5 mL of serum frozen in plastic vial.
  • Draw date is required on request form for processing.

Storage/Stability

Specimen Type Temperature Time
Serum Refrigerated 3 days
  Frozen (preferred) 1 month
  Ambient 12 hours

 

Reject Due To

  • Heat-inactivated specimen
  • Specimens frozen/thawed more than twice
  • Grossly hemolyzed specimen

Reference Values

Negative (reported as positive or negative)
 

Only repeatedly reactive specimens are reported as positive.

Day(s) Test Set Up

Daily

Test Classification and CPT Coding

86704 - anti-HBc, total

LOINC Code Information

Reporting Name LOINC Code
HBcAb, Total 13952-7