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Test Code Billings Clinic: 8509 Complete Islet Autoantibody Screen (GAA, IA-2, IAA, ZnT8), Serum

Performing Laboratory

Barbara Davis Center for Childhood Diabetes

Useful For

  • These autoantibodies may be ordered when a person is newly diagnosed with diabetes and the health practitioner wants to distinguish between type 1 and type 2 diabetes. 
  • These tests may be used when the diagnosis is unclear in diabetics who have been diagnosed as type 2 but who have great difficulty in controlling their glucose levels with standard treatments.

Specimen Requirements

  • Submit 2 mL of serum from a plain red top or red gel.
  • Allow blood to clot prior to centrifugation.
  • Transfer serum to a plastic pour off tube.
  • Send by overnight mail, refrigerated.
  • All tests must be accompanied by a Barbara Davis Childhood Diabetes Test Request (See Resources)

Reference Values

GAA

Normal:      < 20

Elevated:    > 25

 

IA-2

Normal:      < 5

Elevated:    > 7

 

IAA

Normal:      < 0.011

Elevated:    > 0.013

 

ZnT8

Normal:      < 0.021

Elevated:    > 0.030

 

Day(s) Test Set Up

Daily

 

Turn Around Time:  within 1 week

Test Classification and CPT Coding

83516 - GAA

86341 - IA2

86337 - IAA

86849 - ZnT8