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Test Code Billings Clinic: 8616 Mayo: B2M Beta-2-Microglobulin, Serum

Reporting Name

Beta-2-Microglobulin, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Prognosis assessment of multiple myeloma

 

Evaluation of renal tubular disorders

Method Name

Nephelometry


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

1.21-2.70 mcg/mL

Interpretation

A serum beta-2-microglobulin (beta-2-M) value of less than 4 mcg/mL is a good prognostic factor in patients with multiple myeloma. In a study of pretreatment serum beta-2-M levels in 100 patients with myeloma, it was reported that the median survival of patients with values greater than 4 mcg/mL was 12 months, whereas median survival for patients with values less than 4 mcg/mL was 43 months.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 2 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82232

LOINC Code Information

Test ID Test Order Name Order LOINC Value
B2M Beta-2-Microglobulin, S 1952-1

 

Result ID Test Result Name Result LOINC Value
B2M Beta-2-Microglobulin, S 1952-1

Forms

If not ordering electronically, complete, print, and send Renal Diagnostics Test Request (T830)

Testing Algorithm

For more information, see Multiple Myeloma: Laboratory Screening