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Test Code Billings Clinic: 8789 Mayo: C1Q Complement C1q, Serum

Reporting Name

Complement C1q, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessment of an undetectable total complement (CH50) level

 

Diagnosing congenital C1 (first component of complement) deficiency

 

Diagnosing acquired deficiency of C1 inhibitor

Method Name

Nephelometry


Specimen Required


Patient Preparation: Fasting for 12 hours

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial


Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  21 days

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

Reference Values

12-22 mg/dL

Interpretation

An undetectable C1q in the presence of an absent total complement (CH50) and normal C2, C3, and C4 suggests a congenital C1 (first component of complement) deficiency.

 

A low C1q in combination with a low C1 inhibitor and low C4 suggests an acquired C1 inhibitor deficiency.

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86160

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C1Q Complement C1q, S 4478-4

 

Result ID Test Result Name Result LOINC Value
C1Q Complement C1q, S 4478-4