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Test Code Billings Clinic: 8920 Hepatitis Bc Antibody, IgM (Anti-HBc, IgM), Serum

Important Note

The performance of the assay has not been established for patients less than 2 years of age.

Results from patients taking biotin supplements or receiving high-dose biotin therapy should be interpreted with caution due to possible interference with this test.

Performing Laboratory

Billings Clinic Laboratory: Chemistry

 

See “Viral Hepatitis Serologic Profiles—Billings Clinic Laboratory” under "Resources"

Useful For

  • Diagnosis of acute hepatitis B infection
  • Identifying acute hepatitis B virus (HBV) infection in the serologic window period when hepatitis B surface antigen and anti-hepatitis B surface are negative
  • Differentiation between acute and chronic/past hepatitis B infection in the presence of positive anti-hepatitis B core

Methodology

Chemiluminescent Microparticle Immunoassay (CMIA)

Specimen Requirements

Serum should be physically separated from cells as soon as possible with a maximum limit of two hours from the time of collection.

 

  • Draw blood in a serum gel tube(s).
  • Spin down and send 2 mL of serum frozen in plastic vial.
  • Draw date is required on request form for processing.

Storage/Stability

Specimen Type Temperature Time
Serum Refrigerated 2 days
  Frozen (preferred) 1 month

 

Reject Due To

  • Heat-inactivated specimen
  • Grossly hemolyzed specimen

Reference Values

Negative (reported as positive or negative)
 

Only repeatedly reactive specimens are reported as positive.

Day(s) Test Set Up

Daily

Test Classification and CPT Coding

86705 - Hepatitis B core antibody (HBcAb); IgM antibody

LOINC Code Information

Reporting Name LOINC Code
HBcAb, IgM 24113-3