Test Code Billings Clinic: 8924 Mayo: VDSF VDRL, Spinal Fluid
Reporting Name
VDRL, CSFPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Aiding in the diagnosis of neurosyphilis
Method Name
Flocculation/Agglutination
Ordering Guidance
For assessment of intrathecally synthesized Treponema pallidum antibodies in spinal fluid (CSF) (ie, the method corrects for any passive diffusion of antibodies from serum into the CSF), order NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.
Specimen Required
Collection Container/Tube: Sterile vial
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Submit specimen collected in vial 2, if possible. If not, note which vial from which the aliquot was obtained.
Specimen Type
CSFSpecimen Minimum Volume
0.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF | Frozen (preferred) | 14 days |
| Refrigerated | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
Reference Values
Negative
Reference values apply to all ages.
Interpretation
A positive VDRL result on spinal fluid is highly specific for neurosyphilis.
A single negative VDRL result should not be used to exclude neurosyphilis and repeat testing on a new specimen may be necessary.
Positive results will be titered.
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86592
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| VDSF | VDRL, CSF | 5290-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 9028 | VDRL, CSF | 5290-2 |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| VDSFQ | VDRL Titer, CSF | No | No |
Testing Algorithm
If this test is positive, a VDRL titer will be performed at an additional charge.