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Test Code Billings Clinic: 8951 Mayo: GBM Glomerular Basement Membrane Antibodies, IgG, Serum

Reporting Name

Glomerular Basement Membrane IgG Ab

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluating patients with clinical features of anti-glomerular basement disease, including rapidly progressive glomerulonephritis or pulmonary hemorrhage

Method Name

Multiplex Flow Immunoassay


Ordering Guidance


If patient is being evaluated for autoimmune skin disease, order CIFS / Cutaneous Immunofluorescence Antibodies (IgG), Serum for evaluation of anti-intercellular substance (ICS) and antibasement membrane zone (BMZ) antibodies.



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Reference Values

<1.0 U (negative)

≥1.0 U (positive)

Reference values apply to all ages.

Interpretation

A positive result for anti-glomerular basement (GBM) antibody is consistent with the diagnosis of anti-GBM disease, in patients with the appropriate clinical presentation.

Day(s) Performed

Monday through Friday

Report Available

2 to 3 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83516

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GBM Glomerular Basement Membrane IgG Ab 31254-6

 

Result ID Test Result Name Result LOINC Value
GBM Glomerular Basement Membrane IgG Ab 31254-6

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.