Test Code Billings Clinic: 8985 Mayo: CDP Chlordiazepoxide and Metabolite, Serum
Test Down Notes
This test is temporarily unavailable due to instrumentation issues. As an alternate, order ZW86 (1080SP). For additional details, see test update here.
Reporting Name
Chlordiazepoxide and metabolite, SPerforming Laboratory
Mayo Clinic Laboratories in RochesterUseful For
Monitoring chlordiazepoxide therapy
Assessing toxicity
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Shipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube: Red top
Submission Container/Tube: Amber vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into amber vial within 2 hours of collection.
Specimen Type
Serum RedSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum Red | Refrigerated (preferred) | 14 days | LIGHT PROTECTED |
Frozen | 14 days | LIGHT PROTECTED | |
Ambient | 24 hours | LIGHT PROTECTED |
Reject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Reference Values
Therapeutic concentration:
Chlordiazepoxide: 400-3,000 ng/mL
Nordiazepam: 100-500 ng/mL
Interpretation
Chlordiazepoxide and nordiazepoxide combined concentrations above 5000 ng/mL have been associated with toxicity.
Day(s) Performed
Monday, Wednesday
Report Available
2 to 7 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CDP | Chlordiazepoxide and metabolite, S | 33060-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8610 | Chlordiazepoxide | 3457-9 |
37321 | Nordiazepam | 3537-8 |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Neurology Specialty Testing Client Test Request (T732)
-Therapeutics Test Request (T831)