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Test Code Billings Clinic: 9092 Mayo: ASPAG Aspergillus (Galactomannan) Antigen, Serum

Reporting Name

Aspergillus Ag, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Aiding in the diagnosis of invasive aspergillosis

 

Assessing response to therapy

Method Name

Enzyme Immunoassay (EIA)


Ordering Guidance


For bronchoalveolar lavage specimens, order ASPBA / Aspergillus Antigen, Bronchoalveolar Lavage.



Specimen Required


Container/Tube: Serum gel (red-top tubes are not acceptable)

Specimen Volume: 1.5 mL

Collection Instructions:

1. Avoid exposure of specimen to atmosphere to prevent sample contamination from environment.

2. Centrifuge and send specimen in original tube. Do not aliquot or open tube.


Specimen Type

Serum SST

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Refrigerated (preferred) 14 days SERUM GEL TUBE
  Frozen  14 days SERUM GEL TUBE

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Reference Values

<0.5 index

Reference values apply to all ages.

Interpretation

A positive result supports a diagnosis of invasive aspergillosis (IA). Positive results should be considered in conjunction with other diagnostic procedures, such as microbiologic culture, histological examination of biopsy specimens, and radiographic evidence. See Cautions.

 

A negative result does not rule out the diagnosis of IA. Repeat testing is recommended if the result is negative but IA is clinically suspected. Patients at risk of IA should have a baseline serum tested and should be monitored twice a week for increasing galactomannan antigen levels.

 

Galactomannan antigen levels may be useful in the assessment of therapeutic response. Antigen levels decline in response to antimicrobial therapy.

Day(s) Performed

Monday through Friday, Sunday

Report Available

1 to 4 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87305 

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ASPAG Aspergillus Ag, S 44357-2

 

Result ID Test Result Name Result LOINC Value
84356 Aspergillus Ag, S 44357-2