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Test Code Billings Clinic: 9323 Mayo: LKM Liver/Kidney Microsome Type 1 Antibodies, Serum

Reporting Name

Liver/Kidney Microsome Type 1 Ab, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of patients with liver disease of unknown etiology

 

Evaluation of patients with suspected autoimmune hepatitis

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat treated Reject

Reference Values

≤20.0 Units (Negative)

20.1-24.9 Units (Equivocal)

≥25.0 Units (Positive)

Reference values apply to all ages.

Interpretation

Seropositivity for anti-liver/kidney microsomal antibodies type 1 antibodies is consistent with a diagnosis of autoimmune hepatitis type 2, in patients with compatible clinical symptoms and histopathology.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

2 to 4 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86376

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LKM Liver/Kidney Microsome Type 1 Ab, S 32220-6

 

Result ID Test Result Name Result LOINC Value
LKM Liver/Kidney Microsome Type 1 Ab, S 32220-6

Forms

If not ordering electronically, complete, print, and send 1 of the following with the specimen:

-Gastroenterology and Hepatology Test Request (T728)

-General Request (T239)

Testing Algorithm

For more information see First-Line Screening for Autoimmune Liver Disease Algorithm.