Test Code Billings Clinic: 9654 Mayo: ASPBA Aspergillus Antigen, Bronchoalveolar Lavage
Reporting Name
Aspergillus Ag, BALPerforming Laboratory
Mayo Clinic Laboratories in RochesterUseful For
Aiding in the diagnosis of invasive aspergillosis using bronchoalveolar lavage specimens
Assessing response to therapy
Method Name
Enzyme Immunoassay (EIA)
Ordering Guidance
For serum specimens, order ASPAG / Aspergillus (Galactomannan) Antigen, Serum.
Specimen Required
Container/Tube: Sterile, leak-proof container
Note: Specimen trap collection containers (with suction catheters attached) will be rejected due to high-risk of leakage and contamination upon opening. Avoid use of these for bronchoalveolar lavage specimens.
Specimen Volume: 2 mL
Additional Information: If specimen transfer into an acceptable sterile container is necessary, perform specimen transfer in a biosafety cabinet. Place container in separate sealed plastic bag.
Specimen Type
LavageSpecimen Minimum Volume
1.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Lavage | Refrigerated (preferred) | 14 days | |
Frozen | 14 days |
Reject Due To
Bronchial washing | Reject |
Thick/viscous/mucoid specimens | Reject |
Specimen in a non-leak proof container | Reject |
Reference Values
<0.5 Index
Interpretation
A positive result in bronchoalveolar lavage (BAL) fluid supports a diagnosis of invasive, pulmonary aspergillosis. Positive results should be considered in conjunction with other diagnostic procedures, such as microbiologic culture, histological examination of biopsy specimens, and radiographic evidence (see Cautions).
A negative result in BAL fluid does not rule out the diagnosis of invasive aspergillosis (IA). Patients at risk of IA should be monitored twice a week for Aspergillus antigen levels in serum until determined to be clinically unnecessary.
Aspergillus antigen levels typically decline in response to effective antimicrobial therapy.
Day(s) Performed
Monday through Friday, Sunday
Report Available
1 to 2 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
87305
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ASPBA | Aspergillus Ag, BAL | 62467-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
61009 | Aspergillus Ag, BAL | 62467-6 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.