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Test Code Billings Clinic: 9668 Mayo: FIGER Immunoglobulin E (IgE) Receptor Antibody, Serum

Performing Laboratory

National Jewish Health

Useful For

  • The test detects functional autoantibodies to the Fc-epsilon receptor (high affinity IgE receptor) or to IgE and is useful in the evaluation of chronic urticaria.
  • In the presence of antibody to the FceR1, basophils degranulate resulting in the increased expression of a specific basophil marker. The expression of this marker is determined after incubation of susceptible donor basophils with serum from the patient.

Methodology

Flow Cytometry

Specimen Requirements

  • Draw blood in a plain, red-top tube(s).
  • Allow blood to clot and separtate within 1 hour.
  • Spin down and send 1 mL of serum frozen in plastic vial.

Reject Due To

Grossly hemolyzed specimens

Reference Values

< 5%

 

Day(s) Test Set Up

Monday, Thursday

Test Classification and CPT Coding

CPT Code:

88184 - flow cytometry, cell surface, cytoplasmic, or nuclear marker, technical component only; first marker

88185 x 2 - each additional marker

 

Test Classification:

This test uses a kit/reagent designated by the manufacturer as for research use, not for clinical use as well as a reagent that is classified as an analyte specific reagent (ASR). The performance characteristics of this test have been validated by Advanced Diagnostic Laboratories at National Jewish Health. It has not been cleared or approved by the US Food and Drug Administration. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA-88) as qualified to perform high complexity clinical laboratory testing.

 

 

LOINC Code Information

Result ID Reporting Name LOINC Code
Z1297 IgE Receptor Ab In Process