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Test Code CARTA Carbamazepine, Total, Serum

Reporting Name

Carbamazepine, Tot, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring therapy

 

Determining compliance

 

Assessing toxicity

Method Name

Homogeneous Microparticle Agglutination Immunoassay


Ordering Guidance


This test measures carbamazepine only. For assessment of its active metabolite, carbamazepine-10,11-epoxide, which is the predominant form in children, order CARBG / Carbamazepine-10,11-Epoxide, Serum)



Specimen Required


Collection Container/Tube: Red top

Specimen Volume: 0.5 mL

Submission Container/Tube: Plastic vial

Collection Instructions: Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.


Specimen Type

Serum Red

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 7 days
  Frozen  28 days
  Ambient  48 hours

Reject Due To

Gross hemolysis Reject

Reference Values

Therapeutic: 4.0-12.0 mcg/mL

Critical value: ≥15.0 mcg/mL

Interpretation

Dosage adjustments are usually guided by monitoring blood levels. Most patients respond well when the serum concentration is in the range of 4.0 to 12.0 mcg/mL. Toxicity often occurs when levels are greater than or equal to 15.0 mcg/mL.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

80156 

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CARTA Carbamazepine, Tot, S 3432-2

 

Result ID Test Result Name Result LOINC Value
CARTA Carbamazepine, Tot, S 3432-2

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-Therapeutics Test Request (T831)