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Test Code CDTA Carbohydrate Deficient Transferrin, Adult, Serum

Reporting Name

Carb Def Transferrin, Adult, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Indicating chronic alcohol abuse

 

This test is not appropriate for screening patients for congenital disorders of glycosylation.

Method Name

Affinity Chromatography/Mass Spectrometry (MS)


Ordering Guidance


This test is for evaluation of alcohol abuse. If the ordering physician is looking for congenital disorders of glycosylation, order CDG / Carbohydrate Deficient Transferrin for Congenital Disorders of Glycosylation, Serum.



Necessary Information


1. Patient's age is required.

2. Reason for testing is required if patient is younger than 21 years.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Minimum Volume

0.05 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 45 days
  Refrigerated  28 days
  Ambient  7 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

≤0.10

0.11-0.12 (indeterminate)

Interpretation

Patients with chronic alcoholism may develop abnormally glycosylated transferrin isoforms (ie, carbohydrate deficient transferrin: CDT >0.12). CDT results from 0.11 to 0.12 are considered indeterminate.

 

Patients with liver disease due to genetic or nongenetic causes may also have abnormal results.

Day(s) Performed

Wednesday

Report Available

3 to 9 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82373

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDTA Carb Def Transferrin, Adult, S 53803-3

 

Result ID Test Result Name Result LOINC Value
31714 Mono-oligo/Di-oligo Ratio 35469-6
31715 Interpretation 59462-2

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.