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Test Code CEAPC Carcinoembryonic Antigen (CEA), Pancreatic Cyst Fluid

Reporting Name

CEA, Pancreatic Cyst

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

When used in conjunction with imaging studies, cytology, and other pancreatic cyst fluid tumor markers:

-Distinguishing between mucinous and nonmucinous pancreatic cysts

-Determining the likely type of malignant pancreatic cyst

Method Name

Immunoenzymatic Assay


Ordering Guidance


This test should not be ordered for pancreatic fluid of noncyst origin (eg, pancreatic duct fluid; peripancreatic fluid) since reference values have not been established for this specimen type. For ordering assistance call 800-533-1710.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Container/Tube: Plain, plastic, screw-top tube

Specimen Volume: 1 mL


Specimen Type

Pancreatic Cyst Fluid

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Pancreatic Cyst Fluid Frozen (preferred) 90 days
  Refrigerated  72 hours
  Ambient  24 hours

Reject Due To

Gross hemolysis OK
Hemolysis >5000 mg/dL Reject

Reference Values

An interpretive report will be provided.

Interpretation

A pancreatic cyst fluid carcinoembryonic antigen (CEA) concentration greater than or equal to 200 ng/mL is very suggestive for a mucinous cyst but is not diagnostic. The sensitivity and specificity for mucinous lesions are approximately 62% and 93%, respectively, at this concentration. Cyst fluid CEA concentrations less than 5 ng/mL indicate a low risk for a mucinous cyst and are more consistent with serous cystadenoma, fluid collections complicating pancreatitis, cystic neuroendocrine tumor, or metastatic lesions. CEA values between these extremes have limited diagnostic value.

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82378

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CEAPC CEA, Pancreatic Cyst 97747-0

 

Result ID Test Result Name Result LOINC Value
CEAP CEA, Pancreatic Cyst 97747-0
SITE6 Site 39111-0

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.